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Research Grants

Division of Cardiovascular Medicine
RESEARCH GRANTS

National Institutes of Health Grants

  • Assessment of Perfusion Reserve and Effects of Exercise in Microvascular Angina. 2015; NHLBI; 5 K23 HL1 119620 03 (PI: Jamie Bourque)
  • A Bioengineering Approach to Gene Therapy for Peripheral Arterial Disease; 2015; NHLBI; 5 RO1 HL 116455 02 (PI: Brian H. Annex, et al)
  • Microrna 93 in Peripheral Arterial Disease; 2015; NHLBI; 5 RO1 HL 121635 02 (PI: Brian H. Annex)
  • Reuse of ZD045for Patients with Symptomatic PAD; 2014; NCATS; 5 UH3 TR000959 02 (PI: Brian H. Annex)
  • Ultrasound-triggered Drug Delivery with Acoustically Active Red Blood Cells; 2014; NIBIB; 5 R21 EB016752 02 (PI: Alexander Klibanov)
  • Training in Cardiovascular Imaging Research; 2015; NBIB; 5 T32 EB0003841 10 (PI: Christopher M. Kramer)
  • Comprehensive Magnetic Resonance in PAD; 2015; NHLBI; 5 R01 HL075792 11 (PI: Christopher M. Kramer)
  • HCMR Novel Markers of Prognosis in Hypertrophic Cardiomyopathy; 2015; NHLBI; 5 U01 HL117006 03 (PI: Christopher M. Kramer)
  • B-1A Lymphocytes in Atherocclerosis; 2015; NHLBI; 5 PO1 HL055798 19 7226 (PI: Coleen A. McNamara)
  • Genetic Regulation of B Lymphocyte Aortic Homing and Atheroprotection; 2014; NHLBI 5 R01 HL 107490 04 (PI: Coleen A. McNamara)
  • Predictive Informatics Monitoring in the Neonatal Intensive Care Unit; 2015; NICHD; 5 R01 HD072071 02 (PI: J. Randall Moorman)
  • Quantitative Adenosine Stress CMR with Spiral Pulse Sequences; 2015; NHLB;I 5 K23 HL112910 04 (PI: Michael Salerno)
  • Muscle-Mediated Protection Against MODS; 2015; NIGMS; 1 R01 GM114804840 01 (PI: Zhen Yan)
  • P38 MPAK Regulator of Muscle Contraction and Function; 2015; NIAMS; 5 R01 AR050429 11 (PI: Zhen Yan)

Other Research Grants

  • Exercise Capacity: Predictors of exercise capacity during stress exercise electrocardiography. (PI: Jamie Bourque, with Kevin Driver)
  • Lantheus 302: Assessment of myocardial perfusion using positron emission tomography (PET) imaging or flurpiridaz f18 injection in patients with known or suspected coronary heart disease (PI: Jamie Bourque)
  • MRI-CT: Prevalence and correlation of abnormal flow reserve by stress CMR and non-obstructive CAD by cardiac CT in symptomatic diabetics: what is the optimal risk satisfaction method? (PI: Jamie Bourque)
  • PET-LVH: Noninvasive detection of early metabolic remodeling in left ventricular hypertrophy. (PI: Jamie Bourque)
  • EXERRT (Astellas): Exercise to Regadenoson in Recovery Trial (PI: Jamie Bourque)
  • GE HEALTHCARE: An Open-Label, Multicenter, Phase 4 Study to Demonstrate the Prognostic Usefulness of Andreview Scintigraphy for Identifying Subjects with Heart Failure who will Experience Death during 60 months follow-up. (PI: Jamie Bourque)
  • Astellas Scientific and Medical Affairs, Inc. Assessment of Myocardial Flow Reserve and Effects of Exercise Training in Patients with Angina and Negative Coronary Angiograms. (PI: Jamie Bourque)
  • ACCELERATE: Assessment of clinical effects of cholesterylester transfer protein inhibition with Evacetrapib in patients at a high-risk for vascular outcomes. (PI: Lawrence Gimple)
  • Pegasus: A randomized, double-blind, placebo-controlled, parallel group, multinational trial to assess the prevention of thrombotic events with ticagrelor compared to placebo on a background of acetyl salicylic acid (ASA) therapy in patients with history of myocardial infarction. (PI: Lawrence Gimple)
  • Pharmaceutical Research Associates, Inc. OPUS Registry Opsumit (Macitentan) Users Registry. (PI: Jamie Kennedy)
  • CAP2: Continued access to PREVAIL-CAP2 – Watchman device in left atrial appendage for stroke prevention in AFIB patients. (PI: Scott Lim)
  • COAPT: Clinical outcomes assessment of the MitraClip percutaneous therapy for high surgical risk patients in functional mitral regurgitation patients. (PI: Scott Lim)
  • GORE-ASD: A study to evaluate safety and efficacy in the treatment of transcatheter closure of ostium secundum atrial septal defects using Gore septal occluder. Pediatric and adult patients. (PI: Scott Lim)
  • REALISM: A continued access registry of the Evalve MitraClip system – EVEREST II real-world expanded multicenter study of the MitraClip system. Patients with severe degenerative or functional mitral insufficiency undergo MitraClip implantation. (PI: Scott Lim)
  • Direct Flow Medical, Inc. SALUS – The Direct Flow Medical Transcatheter Aortic Valve Replacement System a US Pivotal Trial. (PI: Scott Lim)
  • Claret Medical, Inc. Claret Medical Sentinel IDE Study (PI: Scott Lim)
  • St. Jude Medical, Cardiology Division, Inc. Closure of A trial Septal Defects with the Amplatzer Septal Occluder (AS) Post Market Surveillance Study (PI: Scott Lim)
  • Bon Secours Richmond Health Care Foundation. Medtronic SURTAVI Study. (PI: Scott Lim)
  • EXCEL: Evaluation of XIENCE PRIME or XIENCE V versus coronary artery bypass surgery for effectiveness of left main revascularization. (PI: Michael Ragosta)
  • PreSERVE AMI: A prospective randomized double-blinded, placebo-controlled phase II trial of intra-coronary infusion of AMR001, a bone marrow-derived autologous CD34+ selected cell product in patients with acute myocardial infarction and low LVEF post STEMI. (PI: Michael Ragosta)
  • Resolute Integrity: A post-approval study of the Medtronic Resolute Integrity Zotarolimus-Eluting Coronary Stent System in the treatment of de novo lesions in native coronary arteries with a reference vessel diameter of 2.25mm to 4.2mm. (PI: Michael Ragosta)
  • Hamilton Health Sciences Corp. COMPLETE MI (PI: Michael Ragosta)
  • Inspire MD. MGuard Prime Stent System Clinical Trial in Patients with Acute ST Elevation Myocardial Infarction, IMD-10 (PI: Michael Ragosta).
  • Biotronik, Inc. BIOTRONIX-BIOF Clinical Protocol for the BIOFLOW-V study (PI: Michael Ragosta)
  • Leland Stanford Junior University. Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) 3 Trial. (PI: Michael Ragosta).
  • Cardiac Assist, Inc. CardiacAssist TandemHeart Theme Registry (PI: Michael Ragosta).
  • Corindus, Inc. CorPath Regional Preseptorship Agreement (PI: Michael Ragosta).
  • Biomet. MarrowStim PAD Kit for the Treatment of Critical Limb Ischemia (CLI) in Submects with Advance Peripheral Arterial Disease (PAD). (PI: Aditya Sharma)
  • Portola Pharmaceuticals, Inc. Multicenter, randomized, active-controlled efficacy and safety study comparing extended uration betrizaban with standard of care enoxaparin for the prevention of venous thromboembolism in acute medically ill patients. (PI: Aditya Sharma).
  • GLORIA: Global registry on long-term oral anti-thrombotic treatment in patients with atrial fibrillation. (PI: Allan Simpson)
  • GORE REDUCE: Gore Helex Septal Occluder and antiplatelet medical management for reduction of recurrent stroke or imaging-confirmed TIA in patients with patent foramen ovale (PFO). (PI: Nina Solenski)