Menu Search Icon

Search

UVA Department of Medicine: FY 2015 Annual Report

Publications

Division of Endocrinology & Metabolism
PUBLICATIONS (July 2014 – June 2015)

During FY 2015, faculty members from the division authored
57 peer-reviewed publications, including the following:

NEJM-Santen-article


The division’s Richard Santen, MD, together with colleagues from the Mayo Clinic and Vanderbilt University, published an article on “Atypical hyperplasia of the breast–risk assessment and management options,” in a January 2015 issue of the New England Journal of Medicine.

  1. Zhao L, Fu Z, Wu J, Aylor KW, Barrett EJ, Cao W, Liu Z. Globular adiponectin ameliorates metabolic insulin resistance via AMPK-mediated restoration ofmicrovascular insulin responses. J Physiol. 2015 Jun 24. doi: 10.1113/JP270371. [Epub ahead of print]
  2. Li C, Siragy HM. (Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose. Am J Physiol Endocrinol Metab. 2015 Jun 16:ajpendo.00603.2014. doi: 10.1152/ajpendo.00603.2014. [Epub ahead of print]
  3. Sharma PR, Mackey AJ, Dejene EA, Ramadan JW, Langefeld CD, Palmer ND, Taylor KD, Wagenknecht LE, Watanabe RM, Rich SS, Nunemaker CS. An islet-targeted genome-wide association scan identifies novel genes implicated in cytokine-mediated islet stress in type 2 diabetes. 2015 May 27:en20151203. [Epub ahead of print]
  4. Hargett SR, Walker NN, Hussain SS, Hoehn KL, Keller SR. Deletion of the Rab GAP Tbc1d1 modifies glucose, lipid and energy homeostasis in mice. Am J Physiol Endocrinol Metab. 2015 May 26:ajpendo.00007.2015. doi: 10.1152/ajpendo.00007.2015. [Epub ahead of print]
  5. Qureshi FM, Dejene EA, Corbin KL, Nunemaker CS. Stress-induced dissociations between intracellular calcium signaling and insulin secretion in pancreatic islets. Cell Calcium. 2015 May;57(5-6):366-75. doi: 10.1016/j.ceca.2015.03.002. Epub 2015 Mar 23.
  6. Wang H, Wang AX, Aylor K, Barrett EJ. Caveolin-1 phosphorylation regulates vascular endothelial insulin uptake and is impaired by insulin resistance in rats. 2015 Jun;58(6):1344-53. doi: 10.1007/s00125-015-3546-3. Epub 2015 Mar 10.
  7. Sheng C, Liu Z. Vascular function, insulin action, and exercise: an intricate interplay. Trends Endocrinol Metab. 2015 Jun;26(6):297-304. doi: 10.1016/j.tem.2015.02.002. Epub 2015 Feb 23. Review.
  8. Chen H, Wang JP, Santen RJ, Yue W. Adenosine monophosphate activated protein kinase (AMPK), a mediator of estradiol-induced apoptosis in long-term estrogen deprived breast cancer cells. 2015 Jun;20(6):821-30. doi: 10.1007/s10495-015-1111-7.
  9. Matavelli LC, Siragy HM. AT2 receptor activities and pathophysiological implications. J Cardiovasc Pharmacol. 2015 Mar;65(3):226-32. doi: 10.1097/FJC.0000000000000208.
  10. Brown SA, Kovatchev BP, Breton MD, Anderson SM, Keith-Hynes P, Patek SD, Jiang B, Ben Brahim N, Vereshchetin P, Bruttomesso D, Avogaro A, Del Favero S, Boscari F, Galasso S, Visentin R, Monaro M, Cobelli C. Multinight “bedside” closed-loop control for patients with type 1 diabetes. Diabetes Technol Ther. 2015 Mar;17(3):203-9. doi: 10.1089/dia.2014.0259. Epub 2015 Jan 16.
  11. Matavelli LC, Zatz R, Siragy HM. A nonpeptide angiotensin II type 2 receptor agonist prevents renal inflammation in early diabetes. J Cardiovasc Pharmacol. 2015 Apr;65(4):371-6. doi: 10.1097/FJC.0000000000000207.
  12. Santen RJ, Demers LM, Ziegler RG. Workshop on measuring estrogen exposure and metabolism: Summary of the presentations. 2015 Jul;99(Pt A):1-7. doi: 10.1016/j.steroids.2014.12.012. Epub 2014 Dec 30. No abstract available.
  13. Hartmann LC, Degnim AC, Santen RJ, Dupont WD, Ghosh K. Atypical hyperplasia of the breast–risk assessment and management options. N Engl J Med. 2015 Jan 1;372(1):78-89. doi: 10.1056/NEJMsr1407164. No abstract available.
  14. Gray SM, Meijer RI, Barrett EJ. Insulin regulates brain function, but how does it get there? 2014 Dec;63(12):3992-7. doi: 10.2337/db14-0340. Review.
  15. Cefalu WT, Nair KS, Seaquist ER, Zierath J, Boulton AJ, LeRoith D, Harrell RM, Grunberger G, Wartofsky L, Gore AC, Wierman ME, Hammes SR, Lange CA, Santen RJ. Statement of principle. Endocr Rev. 2014 Dec;35(6):850. doi: 10.1210/er.2014-1089. Epub 2014 Nov 3. No abstract available.
  16. Nass R, Nikolayev A, Liu J, Pezzoli SS, Farhy LS, Patrie J, Gaylinn BD, Heiman M, Thorner MO. The level of circulating octanoate does not predict ghrelin O-acyl transferase (GOAT)-mediated acylation of ghrelin during fasting. J Clin Endocrinol Metab. 2015 Jan;100(1):E110-3. doi: 10.1210/jc.2014-1318.
  17. Santen RJ, Yue W, Wang JP. Estrogen metabolites and breast cancer. 2015 Jul;99(Pt A):61-66. doi: 10.1016/j.steroids.2014.08.003. Epub 2014 Aug 26. Review.
  18. Quadri S, Siragy HM. Regulation of (pro)renin receptor expression in mIMCD via the GSK-3β-NFAT5-SIRT-1 signaling pathway. Am J Physiol Renal Physiol. 2014 Sep 1;307(5):F593-600. doi: 10.1152/ajprenal.00245.2014. Epub 2014 Jul 2.
  19. Nass R, Liu J, Patrie J, Pezzoli SS, Farhy LS, Gaylinn BD, Thorner MO. Four-hour infusion of hydrocortisone does not suppress the nocturnal increase of circulating acyl- or desacyl-ghrelin concentrations in healthy young adults. J Clin Endocrinol Metab. 2014 Sep;99(9):E1696-700. doi: 10.1210/jc.2014-1210. Epub 2014 Jun 25.
  20. Kemp BA, Howell NL, Gildea JJ, Keller SR, Padia SH, Carey RM. AT₂ receptor activation induces natriuresis and lowers blood pressure. Circ Res. 2014 Jul 18;115(3):388-99. doi: 10.1161/CIRCRESAHA.115.304110. Epub 2014 Jun 5.
  21. Kemp BA, Howell NL, Gildea JJ, Padia SH. Intrarenal ghrelin receptor antagonism prevents high-fat diet-induced hypertension in male rats. 2014 Jul;155(7):2658-66. doi: 10.1210/en.2013-2177. Epub 2014 May 5.
  22. Collins JS, Beller JP, Burt Solorzano C, Patrie JT, Chang RJ, Marshall JC, McCartney CR. Blunted day-night changes in luteinizing hormone pulse frequency in girls with obesity: the potential role of hyperandrogenemia. J Clin Endocrinol Metab. 2014 Aug;99(8):2887-96. doi: 10.1210/jc.2013-3258. Epub 2014 Apr 29.
  23. Chai W, Zhang X, Barrett EJ, Liu Z. Glucagon-like peptide 1 recruits muscle microvasculature and improves insulin’s metabolic action in the presence of insulin resistance. 2014 Aug;63(8):2788-99. doi: 10.2337/db13-1597. Epub 2014 Mar 21.
  24. Nunemaker CS, Satin LS. Episodic hormone secretion: a comparison of the basis of pulsatile secretion of insulin and GnRH. 2014 Sep;47(1):49-63. doi: 10.1007/s12020-014-0212-3. Epub 2014 Mar 8. Review.
  25. Subaran SC, Sauder MA, Chai W, Jahn LA, Fowler DE, Aylor KW, Basu A, Liu Z. GLP-1 at physiological concentrations recruits skeletal and cardiac muscle microvasculature in healthy humans. Clin Sci (Lond). 2014 Aug;127(3):163-70. doi: 10.1042/CS20130708.
In This Section down-arrow
Menu