Ahmed T, Mahfuz M, Islam MM, Mondal D, Hossain MI, Ahmed AS, Tofail F, Gaffar SA, Haque R, Guerrant RL, Petri WA. The MAL-ED cohort study in Mirpur, Bangladesh. Clin Infect Dis 2014 11/01;59 Suppl 4:S280-S286. DOI: 10.1093/cid/ciu458
Archbald-Pannone L, Boone JH, Carman RJ, Lyerly DM, Guerrant RL. Clostridium difficile ribotype 027 is most prevalent among inpatients admitted from long-term care facilities. J Hosp Infect 2014 12;88(4):218-221. DOI: 10.1016/j.jhin.2014.06.016
Archbald-Pannone L, Kolling G, Ren T, Wu M. Microbiota differences in hospitalized patients with Clostridium difficile infection and delirium. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 2015 04;63:S177-S177.
Archbald-Pannone L, McMurry TL, Guerrant RL, Warren CA. Delirium and other clinical factors with Clostridium difficile infection that predict mortality in hospitalized patients. Am J Infect Control 2015 04/24DOI: 10.1016/j.ajic.2015.03.017
Bartelt LA, Guerrant RL. Antibiotics help control rotavirus infections and enhance antirotaviral immunity: are you serious? J Infect Dis 2014 07/15;210(2):167-170. DOI: 10.1093/infdis/jiu153
Bolick DT, Kolling GL, Moore JH, de Oliveira LA, Tung K, Philipson C, Viladomiu M, Hontecillas R, Bassaganya-Riera J, Guerrant RL. Zinc deficiency alters host response and pathogen virulence in a mouse model of enteroaggregative escherichia coli-induced diarrhea. Gut Microbes 2014;5(5):618-627. DOI: 10.4161/19490976.2014.969642
Bonatti HJR, Metzger R, Swenson BR, Pawlowski S, Krell RW, Pruett TL, Brayman KL, Sifri CD, Sawyer RG. Solid organ recipients are at increased risk for recurrent Clostridium difficile colitis. EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA 2014 08;46(4):160-164. DOI: 10.1007/s10353-014-0279-3
Checkley W, White AC, Jaganath D, Arrowood MJ, Chalmers RM, Chen XM, Fayer R, Griffiths JK, Guerrant RL, Hedstrom L, Huston CD, Kotloff KL, Kang G, Mead JR, Miller M, Petri WA, Priest JW, Roos DS, Striepen B, Thompson RC, et al. A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium. Lancet Infect Dis 2015 01;15(1):85-94. DOI: 10.1016/S1473-3099(14)70772-8
Cowardin CA, Kuehne SA, Buonomo EL, Marie CS, Minton NP, Petri WA. Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile. MBio 2015;6(1)DOI: 10.1128/mBio.02386-14
Cowardin CA, Petri WA. Host recognition of Clostridium difficile and the innate immune response. Anaerobe 2014 12;30:205-209. DOI: 10.1016/j.anaerobe.2014.08.014
D’Auria KM, Bloom MJ, Reyes Y, Gray MC, van Opstal EJ, Papin JA, Hewlett EL. High temporal resolution of glucosyltransferase dependent and independent effects of Clostridium difficile toxins across multiple cell types. BMC Microbiol 2015;15:7. DOI: 10.1186/s12866-015-0361-4
Donowitz JR, Petri WA. Pediatric small intestine bacterial overgrowth in low-income countries. Trends Mol Med 2015 01;21(1):6-15. DOI: 10.1016/j.molmed.2014.11.001
Dunning J, Baillie JK, Cao B, Hayden FG. International Severe Acute Respiratory and Emerging, Infection Consortium. Antiviral combinations for severe influenza. Lancet Infect Dis 2014 12;14(12):1259-1270. DOI: 10.1016/S1473-3099(14)70821-7
Eby JC, Gray MC, Hewlett EL. Cyclic AMP-mediated suppression of neutrophil extracellular trap formation and apoptosis by the Bordetella pertussis adenylate cyclase toxin. Infect Immun 2014 12;82(12):5256-5269. DOI: 10.1128/IAI.02487-14
Enfield KB, Huq NN, Gosseling MF, Low DJ, Hazen KC, Toney DM, Slitt G, Zapata HJ, Cox HL, Lewis JD, Kundzins JR, Mathers AJ, Sifri CD. Control of simultaneous outbreaks of carbapenemase-producing enterobacteriaceae and extensively drug-resistant Acinetobacter baumannii infection in an intensive care unit using interventions promoted in the Centers for Disease Control and Prevention 2012 carbapenemase-resistant Enterobacteriaceae Toolkit. Infect Control Hosp Epidemiol 2014 07;35(7):810-817. DOI: 10.1086/676857
Evans EE, Wang XQ, Moore CC. Distance from care predicts in-hospital mortality in HIV-infected patients with severe sepsis from rural and semi-rural Virginia, USA. Int J STD AIDS 2015 04/29DOI: 10.1177/0956462415584489
Ghanchi NK, Khan E, Farooqi JQ, Fasih N, Dojki M, Hughes MA. Knowledge and practices of laboratory workers on standardized antimicrobial susceptibility testing and biosafety practices to prevent the spread of superbugs in Pakistan. Am J Infect Control 2014 09;42(9):1022-1024. DOI: 10.1016/j.ajic.2014.06.006
Gilchrist CA. Entamoeba bangladeshi: An insight. Trop Parasitol 2014 07;4(2):96-98. DOI: 10.4103/2229-5070.138536
Gilmartin AA, Petri WA. Exploring the role of environmental enteropathy in malnutrition, infant development and oral vaccine response. Philos Trans R Soc Lond B Biol Sci 2015 06/19;370(1671)DOI: 10.1098/rstb.2014.0143
Green M, Covington S, Taranto S, Wolfe C, Bell W, Biggins SW, Conti D, DeStefano GD, Dominguez E, Ennis D, Gross T, Klassen-Fischer M, Kotton C, LaPointe-Rudow D, Law Y, Ludrosky K, Menegus M, Morris MI, Nalesnik MA, Pavlakis M, et al. Donor-derived transmission events in 2013: a report of the Organ Procurement Transplant Network Ad Hoc Disease Transmission Advisory Committee. Transplantation 2015 02;99(2):282-287. DOI: 10.1097/TP.0000000000000584
Hayden FG, Farrar J, Peiris JS. Towards improving clinical management of Middle East respiratory syndrome coronavirus infection. Lancet Infect Dis 2014 07;14(7):544-546. DOI: 10.1016/S1473-3099(14)70793-5
Heysell SK. Having walked the path. Ann Intern Med 2014 09/02;161(5):374-375. DOI: 10.7326/M14-0326
Heysell SK, Ahmed S, Ferdous SS, Khan MS, Rahman SM, Gratz J, Rahman MT, Mahmud AM, Houpt ER, Banu S. Quantitative drug-susceptibility in patients treated for multidrug-resistant tuberculosis in Bangladesh: implications for regimen choice. PLoS One 2015;10(2):e0116795. DOI: 10.1371/journal.pone.0116795
Heysell SK, Moore JL, Peloquin CA, Ashkin D, Houpt ER. Outcomes and use of therapeutic drug monitoring in multidrug-resistant tuberculosis patients treated in Virginia, 2009-2014. Tuberc Respir Dis (Seoul) 2015 04;78(2):78-84. DOI: 10.4046/trd.2015.78.2.78
Hoffman PS, Bruce AM, Olekhnovich I, Warren CA, Burgess SL, Hontecillas R, Viladomiu M, Bassaganya-Riera J, Guerrant RL, Macdonald TL. Preclinical studies of amixicile, a systemic therapeutic developed for treatment of Clostridium difficile infections that also shows efficacy against Helicobacter pylori. Antimicrob Agents Chemother 2014 08;58(8):4703-4712. DOI: 10.1128/AAC.03112-14
Houpt E, Gratz J, Kosek M, Zaidi AK, Qureshi S, Kang G, Babji S, Mason C, Bodhidatta L, Samie A, Bessong P, Barrett L, Lima A, Havt A, Haque R, Mondal D, Taniuchi M, Stroup S, McGrath M, Lang D, et al. Microbiologic methods utilized in the MAL-ED cohort study. Clin Infect Dis 2014 11/01;59 Suppl 4:S225-S232. DOI: 10.1093/cid/ciu413
Hsiao A, Ahmed AM, Subramanian S, Griffin NW, Drewry LL, Petri WA, Haque R, Ahmed T, Gordon JI. Members of the human gut microbiota involved in recovery from Vibrio cholerae infection. Nature 2014 11/20;515(7527):423-426. DOI: 10.1038/nature13738
Hurt AC, Hui DS, Hay A, Hayden FG. Overview of the 3rd isirv-Antiviral Group Conference–advances in clinical management. Influenza Other Respir Viruses 2015 01;9(1):20-31. DOI: 10.1111/irv.12293
Jimenez Gutierrez E, Pineda V, Calzada JE, Guerrant RL, Lima Neto JB, Pinkerton RC, Saldana A. Enteric parasites and enteroaggregative Escherichia coli in children from Canazas County, Veraguas Province, Panama. Am J Trop Med Hyg 2014 08;91(2):267-272. DOI: 10.4269/ajtmh.13-0438
Jr PWA, Naylor C, Haque R. Environmental enteropathy and malnutrition: do we know enough to intervene? BMC MEDICINE 2014 10/14;12DOI: 10.1186/s12916-014-0187-1
Kau AL, Planer JD, Liu J, Rao S, Yatsunenko T, Trehan I, Manary MJ, Liu TC, Stappenbeck TS, Maleta KM, Ashorn P, Dewey KG, Houpt ER, Hsieh CS, Gordon JI. Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy. Sci Transl Med 2015 02/25;7(276):276ra24. DOI: 10.1126/scitranslmed.aaa487 7
Keusch GT, Denno DM, Black RE, Duggan C, Guerrant RL, Lavery JV, Nataro JP, Rosenberg IH, Ryan ET, Tarr PI, Ward H, Bhutta ZA, Coovadia H, Lima A, Ramakrishna B, Zaidi AK, Hay Burgess DC, Brewer T. Environmental enteric dysfunction: pathogenesis, diagnosis, and clinical consequences. Clin Infect Dis 2014 11/01;59 Suppl 4:S207-S212. DOI: 10.1093/cid/ciu485
Kirkpatrick BD, Colgate ER, Mychaleckyj JC, Haque R, Dickson DM, Carmolli MP, Nayak U, Taniuchi M, Naylor C, Qadri F, Ma JZ, Alam M, Walsh MC, Diehl SA, PROVIDE ST, Petri WA. The “Performance of Rotavirus and Oral Polio Vaccines in Developing Countries” (PROVIDE) study: description of methods of an interventional study designed to explore complex biologic problems. Am J Trop Med Hyg 2015 04;92(4):744-751. DOI: 10.4269/ajtmh.14-0518
Kosek M, Guerrant RL, Kang G, Bhutta Z, Yori PP, Gratz J, Gottlieb M, Lang D, Lee G, Haque R, Mason CJ, Ahmed T, Lima A, Petri WA, Houpt E, Olortegui MP, Seidman JC, Mduma E, Samie A, Babji S, et al. Assessment of environmental enteropathy in the MAL-ED cohort study: theoretical and analytic framework. Clin Infect Dis 2014 11/01;59 Suppl 4:S239-S247. DOI: 10.1093/cid/ciu457
Kpadeh ZZ, Day SR, Mills BW, Hoffman PS. Legionella pneumophila utilizes a single-player disulfide-bond oxidoreductase system to manage disulfide bond formation and isomerization. Mol Microbiol 2015 03;95(6):1054-1069. DOI: 10.1111/mmi.12914
Lee GO, Kosek P, Lima AA, Singh R, Yori PP, Olortegui MP, Lamsam JL, Oliveira DB, Guerrant RL, Kosek M. Lactulose: mannitol diagnostic test by HPLC and LC-MSMS platforms: considerations for field studies of intestinal barrier function and environmental enteropathy. J Pediatr Gastroenterol Nutr 2014 10;59(4):544-550. DOI: 10.1097/MPG.0000000000000459
Lewis JD, Enfield KB, Mathers AJ, Giannetta ET, Sifri CD. The Limits of Serial Surveillance Cultures in Predicting Clearance of Colonization with Carbapenemase-Producing Enterobacteriaceae. Infect Control Hosp Epidemiol 2015 07;36(7):835-837. DOI: 10.1017/ice.2015.57
Lewis JD, Enfield KB, Sifri CD. Hepatitis B in healthcare workers: Transmission events and guidance for management. World J Hepatol 2015 03/27;7(3):488-497. DOI: 10.4254/wjh.v7.i3.488
Lima AA, Oria RB, Soares AM, Filho JQ, de Sousa F, Abreu CB, Bind¡ A, Lima I, Quetz J, Moraes M, Maciel B, Costa H, Leite AM, Lima NL, Mota FS, Di Moura A, Scharf R, Barrett L, Guerrant RL. Geography, population, demography, socioeconomic, anthropometry, and environmental status in the MAL-ED cohort and case-control study Sites in Fortaleza, Ceara, Brazil. Clin Infect Dis 2014 11/01;59 Suppl 4:S287-S294. DOI: 10.1093/cid/ciu438
Liu J, Kabir F, Manneh J, Lertsethtakarn P, Begum S, Gratz J, Becker SM, Operario DJ, Taniuchi M, Janaki L, Platts-Mills J, Haverstick DM, Kabir M, Sobuz SU, Nakjarung K, Sakpaisal P, Silapong S, Bodhidatta L, Qureshi S, Kalam A, et al. Development and assessment of molecular diagnostic tests for 15 enteropathogens causing childhood diarrhoea: a multicentre study. Lancet Infect Dis 2014 08;14(8):716-724. DOI: 10.1016/S1473-3099(14)70808-4
Liu J, Lurain K, Sobuz SU, Begum S, Kumburu H, Gratz J, Kibiki G, Toney D, Gautam R, Bowen MD, Petri WA, Haque R, Houpt ER. Molecular genotyping and quantitation assay for rotavirus surveillance. J Virol Methods 2015 03;213:157-163. DOI: 10.1016/j.jviromet.2014.12.001
MacIntyre J, McTaggart J, Guerrant RL, Goldfarb DM. Early childhood diarrhoeal diseases and cognition: are we missing the rest of the iceberg? Paediatr Int Child Health 2014 11;34(4):295-307. DOI: 10.1179/2046905514Y.0000000141
Madan R, Petri WA. Role of obesity and adipose tissue-derived cytokine leptin during Clostridium difficile infection. Anaerobe 2015 01/29DOI: 10.1016/j.anaerobe.2014.12.009
Mandapati K, Gorla SK, House AL, McKenney ES, Zhang M, Rao SN, Gollapalli DR, Mann BJ, Goldberg JB, Cuny GD, Glomski IJ, Hedstrom L. Repurposing cryptosporidium inosine 5′-monophosphate dehydrogenase inhibitors as potential antibacterial agents. ACS Med Chem Lett 2014 08/14;5(8):846-850. DOI: 10.1021/ml500203p
Marie C, Petri WA. Regulation of virulence of Entamoeba histolytica. Annu Rev Microbiol 2014;68:493-520. DOI: 10.1146/annurev-micro-091313-103550
Mathers AJ. Antibiotics in laboratory medicine, 6th edition. Clin Infect Dis 2015 05/01;60(9):1446-1447. DOI: 10.1093/cid/civ078
Mathers AJ, Peirano G, Pitout JD. Escherichia coli ST131: The quintessential example of an international multiresistant high-risk clone. Adv Appl Microbiol 2015;90:109-154. DOI: 10.1016/bs.aambs.2014.09.002
Mathers AJ, Stoesser N, Sheppard AE, Pankhurst L, Giess A, Yeh AJ, Didelot X, Turner SD, Sebra R, Kasarskis A, Peto T, Crook D, Sifri CD. Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae at a single institution: insights into endemicity from whole-genome sequencing. Antimicrob Agents Chemother 2015 03;59(3):1656-1663. DOI: 10.1128/AAC.04292-14
Mduma ER, Gratz J, Patil C, Matson K, Dakay M, Liu S, Pascal J, McQuillin L, Mighay E, Hinken E, Ernst A, Amour C, Mvungi R, Bayyo E, Zakaria Y, Kivuyo S, Houpt ER, Svensen E. The etiology, risk factors, and interactions of enteric infections and malnutrition and the consequences for child health and development study (MAL-ED): description of the Tanzanian site. Clin Infect Dis 2014 11/01;59 Suppl 4:S325-S330. DOI: 10.1093/cid/ciu439
Moonah SN, Abhyankar MM, Haque R, Petri WA. The macrophage migration inhibitory factor homolog of Entamoeba histolytica binds to and immunomodulates host macrophages. Infect Immun 2014 09;82(9):3523-3530. DOI: 10.1128/IAI.01812-14
Ndusilo ND, Heysell SK, Mpagama SG, Gratz J, Segesela FH, Pazia SJ, Wang XQ, Houpt ER, Kibiki GS. Improvement in plasma drug activity during the early treatment interval among Tanzanian patients with multidrug-resistant tuberculosis. PLoS One 2015;10(3):e0122769. DOI: 10.1371/journal.pone.0122769
Obata F, Subrahmanyam PB, Vozenilek AE, Hippler LM, Jeffers T, Tongsuk M, Tiper I, Saha P, Jandhyala DM, Kolling GL, Latinovic O, Webb TJ. Natural killer T (NKT) cells accelerate Shiga toxin type 2 (Stx2) pathology in mice. Front Microbiol 2015;6:262. DOI: 10.3389/fmicb.2015.00262
Operario DJ, Bristol LS, Liotta J, Nydam DV, Houpt ER. Correlation between diarrhea severity and oocyst count via quantitative PCR or fluorescence microscopy in experimental cryptosporidiosis in calves. Am J Trop Med Hyg 2015 01;92(1):45-49. DOI: 10.4269/ajtmh.14-0488
Orikiriza P, Tibenderana B, Siedner MJ, Mueller Y, Byarugaba F, Moore CC, Evans EE, Bonnet M, Page AL, Bazira J, Boum Y. Low resistance to first and second line anti-tuberculosis drugs among treatment naive pulmonary tuberculosis patients in southwestern Uganda. PLoS One 2015;10(2):e0118191. DOI: 10.1371/journal.pone.0118191
Pholwat S, Liu J, Stroup S, Gratz J, Banu S, Rahman SM, Ferdous SS, Foongladda S, Boonlert D, Ogarkov O, Zhdanova S, Kibiki G, Heysell S, Houpt E. Integrated microfluidic card with TaqMan probes and high-resolution melt analysis to detect tuberculosis drug resistance mutations across 10 genes. MBio 2015;6(2):e02273. DOI: 10.1128/mBio.02273-14
Platts-Mills J, McCormick BJ, Kosek M, Pan WK, Checkley W, Houpt ER, MAL-ED NI. Methods of analysis of enteropathogen infection in the MAL-ED Cohort Study. Clin Infect Dis 2014 11/01;59 Suppl 4:S233-S238. DOI: 10.1093/cid/ciu408
Qin A, Zhang Y, Clark ME, Rabideau MM, Millan Barea LR, Mann BJ. FipB, an essential virulence factor of Francisella tularensis subsp. tularensis, has dual roles in disulfide bond formation. J Bacteriol 2014 10;196(20):3571-3581. DOI: 10.1128/JB.01359-13
Ralston KS, Solga MD, Mackey-Lawrence NM, Somlata, Bhattacharya A, Petri WA Jr. Trogocytosis-like ingestion by Entamoeba histolytica contributes to human cell killing and tissue invasion. Nature (2014) 508:526-530.doi:10.1038/nature13242.
Ramakrishnan G, Chandra NR, Srinivasan N. From workstations to workbenches: Towards predicting physicochemically viable protein-protein interactions across a host and a pathogen. IUBMB Life 2014 11;66(11):759-774. DOI: 10.1002/iub.1331
Ramakrishnan G, Davaakhuu G, Chung WC, Zhu H, Rana A, Filipovic A, Green AR, Atfi A, Pannuti A, Miele L, Tzivion G. AKT and 14-3-3 regulate Notch4 nuclear localization. Sci Rep 2015;5:8782. DOI: 10.1038/srep08782
Ramakrishnan G, Ochoa-Montano B, Raghavender US, Mudgal R, Joshi AG, Chandra NR, Sowdhamini R, Blundell TL, Srinivasan N. Enriching the annotation of Mycobacterium tuberculosis H37Rv proteome using remote homology detection approaches: insights into structure and function. Tuberculosis (Edinb) 2015 01;95(1):14-25. DOI: 10.1016/j.tube.2014.10.009
Ramakrishnan G, Pedersen K, Guenette D, Sink J, Haque R, Petri WA, Herbein J, Gilchrist CA. Utility of recombinant fragment C for assessment of anti-tetanus antibodies in plasma. Diagn Microbiol Infect Dis 2015 05;82(1):11-13. DOI: 10.1016/j.diagmicrobio.2015.01.016
Richard SA, Barrett LJ, Guerrant RL, Checkley W, Miller MA, MAL-ED NI. Disease surveillance methods used in the 8-site MAL-ED cohort study. Clin Infect Dis 2014 11/01;59 Suppl 4:S220-S224. DOI: 10.1093/cid/ciu435
Singh N, Sifri CD, Silveira FP, Miller R, Gregg KS, Huprikar S, Lease ED, Zimmer A, Dummer JS, Spak CW, Koval C, Banach DB, Shroff M, Le J, Ostrander D, Avery R, Eid A, Razonable RR, Montero J, Blumberg E, et al. Cryptococcosis in Patients With Cirrhosis of the Liver and Posttransplant Outcomes. Transplantation 2015 03/24DOI: 10.1097/TP.0000000000000690
Subramanian S, Huq S, Yatsunenko T, Haque R, Mahfuz M, Alam MA, Benezra A, DeStefano J, Meier MF, Muegge BD, Barratt MJ, VanArendonk LG, Zhang Q, Province MA, Petri WA Jr, Ahmed T, Gordon JI. Persistent Gut Microbiota Immaturity in Malnourished Bangladeshi Children. Nature 2014 510,417421(19 June 2014) doi:10.1038/nature13421
Su YH, Warren CA, Guerrant RL, Swami NS. Dielectrophoretic monitoring and interstrain separation of intact Clostridium difficile based on their S(Surface)-layers. Anal Chem 2014 11/04;86(21):10855-10863. DOI: 10.1021/ac5029837
Sun HY, Alexander BD, Huprikar S, Forrest GN, Bruno D, Lyon GM, Wray D, Johnson LB, Sifri CD, Razonable RR, Morris MI, Stoser V, Wagener MM, Singh N. Predictors of immune reconstitution syndrome in organ transplant recipients with cryptococcosis: implications for the management of immunosuppression. Clin Infect Dis 2015 01/01;60(1):36-44. DOI: 10.1093/cid/ciu711
Taniuchi M, Begum S, Uddin MJ, Platts-Mills J, Liu J, Kirkpatrick BD, Chowdhury AH, Jamil KM, Haque R, Petri WA, Houpt ER. Kinetics of poliovirus shedding following oral vaccination as measured by quantitative reverse transcription-PCR versus culture. J Clin Microbiol 2015 01;53(1):206-211. DOI: 10.1128/JCM.02406-14
Verkerke HP, Hanbury B, Siddique A, Samie A, Haque R, Herbein J, Petri WA. Multisite clinical evaluation of a rapid test for Entamoeba histolytica in stool. J Clin Microbiol 2015 02;53(2):493-497. DOI: 10.1128/JCM.02836-14
Verkerke HP, Sobuz SU, Petri WA. Molecular diagnosis of infectious diarrhea: focus on enteric protozoa. Expert Rev Mol Diagn 2014 11;14(8):935-946. DOI: 10.1586/14737159.2014.951035
Wang J, Bartelt L, Yu D, Joshi A, Weinbaum B, Pierson T, Patrizio M, Warren CA, Hughes MA, Donowitz G. Primary cutaneous cryptococcosis treated with debridement and fluconazole monotherapy in an immunosuppressed patient: a case report and review of the literature. Case Rep Infect Dis 2015;2015:131356. DOI: 10.1155/2015/131356
Zumla A, Memish ZA, Maeurer M, Bates M, Mwaba P, Al-Tawfiq J, Denning DW, Hayden FG, Hui DS. Emerging novel and antimicrobial-resistant respiratory tract infections: new drug development and therapeutic options. Lancet Infect Dis 2014 11;14(11):1136-1149. DOI: 10.1016/S1473-3099(14)70828-X